Ecolab to build $190 million medical resins manufacturing site in Landenberg


Ecolab Inc. plans to expand its Purolite business by adding a new biologics resin manufacturing facility in Landenberg, PA. an area near the Delaware state line.

Construction plans for the new facility are underway and will strengthen the security of supply for global pharmaceutical and biotech customers and will support the continued development and production of clinical and commercial-scale therapeutics for patients worldwide, a release stated.

The Philadelphia Business Journal (paywall) reported that the complex will cost $190 million.

“We are excited to announce this new facility, because of what it will mean for our customers and the many healthcare patients around the world who benefit from their innovation. As Purolite continues to grow, we are committed to continued chromatography innovation and dedicated applications support, thus improving the global supply of the high-quality products to produce lifesaving and life-enhancing therapeutics,” said Hayley Crowe, senior vice president and general manager, of Purolite.

Plans for the new U.S. location include the construction of resin production facilities, cleanrooms, laboratories and new office space. Additional land is available at the site for future expansion.


The Landenberg facility will be Purolite’s fourth location in Pennsylvania. Once completed, the new facility is expected to expand production capacity and add more than 150 skilled jobs in the next five years.

“The Commonwealth of Pennsylvania is home to a growing biotech industry, and with Purolite’s expansion in Chester County, we are cementing ourselves as one of the leaders in this rapidly expanding field,” said Gov. Josh Shapiro. “I’m proud that Pennsylvania won this expansion project against other states, and I’m pleased that we will be the home of Purolite’s first U.S. Biologics Division. These types of strategic investments in growing businesses are positioning the Commonwealth as an economic powerhouse, and we will continue to make investments that bring more expansions and good-paying jobs to the Commonwealth.”

The Landenberg location will be Purolite’s sixth global manufacturing facility.

The site will produce agarose chromatography resin for monoclonal antibody and recombinant protein purification, and it will support new modality purification across cell therapy, gene therapy and mRNA. According to the release, the expanded production capacity will allow Purolite to better support innovators worldwide with premier purification resin that will increase yield, optimize productivity, and reduce the time needed to bring lifesaving therapeutics to market.

Eco Lab is best known for its disinfectants used in commercial settings and has acquired water treatment and other companies. Purolite was acquired in 2021.