Biotech venture pairing researchers, companies under way

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The Delaware Biotechnology Institute and the Delaware Economic Development Office announced eight research projects through the recently launched Delaware Bioscience Center for Advanced Technology (Bioscience CAT). CAT grants link researchers from Delaware academic and research institutions with local bioscience companies to create advanced technologies with the potential of moving into the marketplace.

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“These projects are addressing critical issues – ranging from cancer to alternative energies,” said Kelvin Lee, director of the Delaware Biotechnology Institute and Gore Professor of Chemical Engineering at the University of Delaware. “With these talented researchers partnering with local bioscience companies, we are hoping to see a great impact that goes beyond Delaware.”

“These projects are addressing critical issues – ranging from cancer to alternative energies,” said Kelvin Lee, director of the Delaware Biotechnology Institute and Gore Professor of Chemical Engineering at the University of Delaware. “With these talented researchers partnering with local bioscience companies, we are hoping to see a great impact that goes beyond Delaware.”

The first round of CAT grant‐funded projects and partners include (with some details edited)

– “Improving clostridial fermentation of glycerol, and integrating with ChemX technology to demonstrate  lowest cost butanol production” – Terry Papoutsakis of the University of Delaware (lead researcher) and Dynasep, Inc. and Elcriton, Inc.

– “Markers for Asymmetric and Symmetric Colonic Stem Cell Division” – Dr. Bruce Boman of the Center for Translational Cancer Research (lead researcher) and SDIX, Inc.

– “Compatibility of pediatric drug formulations” –Dr. Rob Mason of the Nemours Research Foundation/A.I. DuPont Hospital for Children (lead researcher) and Agilent Technologies.

– ” Biological Mechanisms Leading to High or Low Feed Efficiency in Broiler Chickens”– Behnam Abasht of the University of Delaware (lead researcher) and Heritage Breeders of Perdue Farms.

– “Engineering an anaerobic, low pH fluorescent protein for use in Clostridia cell cultures” –Jeff Caplan of the University of Delaware (lead researcher) and Elcriton, Inc.

– “Bioinformatics Optimization for Recombinant Protein Expression for Vaccines and Therapeutics” – Cathy Wu of the University of Delaware (lead researcher) and Fraunhofer Center for Molecular Biotechnology.

– “Protein Structure Metrics for Synthetic Biologics” – Adam Marsh of the University of Delaware (lead researcher) and Evozym, Inc.

– “Recyclable Porous-SiO2 Supported Transition Metal Catalysts for Active Pharmaceutical Ingredients (APIs)” – Chao Ni of the University of Delaware (lead researcher) and Wilmington PharmaTech.

Bioscience CAT was created in January 2012 to address the technology innovation gap and promote economic development in Delaware. Each project, with an investigator at an academic or research institution in Delaware, has a business in the state providing matching resources to pursue joint research projects.


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