AstraZeneca, Wisconsin company sign drug discovery deal

0
Advertisement

logoCellular Dynamics International, Inc.  announced a Center of Excellence agreement with AstraZeneca to accelerate the pace of drug discovery through the use of human induced pluripotent stem cell (iPSC) lines and tissue cells.

Cellular Dynamics is based in Madison, Wis. AstraZeneca is based in London and has manufacturing and headquarters operations in northern Delaware.

iPSC technology, based on reprogramming adult cells from a simple blood sample or a skin biopsy to a pluripotent stem cell state, shows promise in delivering robust human cell models  in drug discovery and without the ethical concerns over  the use of human embryonic stem cells.

Steve Rees, vice president for  screening sciences & sample management, discovery sciences at AstraZeneca, said, “This agreement with Cellular Dynamics enables AstraZeneca to access world-leading expertise in stem cell technology so that we can better test potential new medicines for safety and efficacy.”

Bob Palay, chief executive officer of CDI, said, “This is the third Center of Excellence agreement we have entered into with a global pharma company, and these partnerships show customer recognition that leveraging CDI’s technical expertise and resources can help accelerate their discoveries. We are excited that AstraZeneca shares our vision that iPSC technology can be transformative. The Center of Excellence agreements show CDI’s leadership in developing best practices to employ human iPSCs to advance healthcare discoveries.”

Under the terms of the Center of Excellence agreement, AstraZeneca will take advantage of commercially available iCell  products and CDI’s recently launched MyCell  Products for iPSC reprogramming and differentiation, and the two parties will collaborate on the development of one or more novel cell type(s).

  AstraZeneca will purchase CDI’s commercially available iCell products, including iCell Cardiomyocytes, iCell Neurons, iCell Endothelial Cells, and iCell Hepatocytes, for use in their safety, discovery, and regenerative medicine programs.

AstraZeneca will rely on CDI’s novel MyCell Products to genetically engineer and manufacture cells from specific patient groups for use as in vitro disease models. In addition, CDI will work in partnership with AstraZeneca toward development of new iPSC-derived cell type(s) to enable novel discovery screening applications. Financial terms of the agreement were undisclosed.

Facebook Comments
Advertisement
SHARE
Previous articleNewark Restaurant Week coming later this month
Next articleBusiness book discussion program announced in Dover
Delaware Business Now is a four-year-old, five-day-a-week newsletter and website operated by Bird Street Media LLC. Publisher and Chief Content Officer is Doug Rainey, a 30-year veteran of business journalism in the state of Delaware.  Business Now focuses on breaking business news in Delaware and immediate adjacent areas with apropriate background and perspective. Also offered exclusively in our FREE newsletter is commentary on state and regional issues. Have a complaint, question or even a compliment? Send an email to drainey@delawarebusinessnow.com. For advertising information, click on the About tab at the top of the home page Our business hours are 8 a.m. to 5 p.m., Monday through Friday. Call us at 302.753.0691.
Advertisement